THERMAL-MECHANICAL COUPLING ANALYSIS AND OPTIMIZATION OF MINE HOIST BRAKE DISC


Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.

Protein tyrosine kinases are important regulators of cellular homeostasis with tightly controlled catalytic activity.Mutations in kinase-encoding genes can relieve the autoinhibitory constraints on kinase activity, can promote malignant transformation, and appear to be a major determinant of response to kinase inhibitor therapy.Missense mutations i

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Cardioneuroablation eliminating cardiac asystole associated with area postrema syndrome: a case report and literature review

BackgroundThere have been few instances of symptomatic bradycardia-arrhythmia in the context of area postrema syndrome (APS), and some of them have been implanted permanent pacemakers.Cardioneuroablation (CNA) has emerged as a viable therapy for the treatment of syncope induced by neutrally mediated bradycardia or atrioventricular block.MethodsWe r

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